Curcumin ( Extract of turmeric) In Diabetes

  • Turmeric has medicinal properties due to its bioactive components isolated from its rhizome.
  • Curcumin is an extract of turmeric wherein it is being extracted in the ratio of 100:2 approx, meaning thereby out of 100kg of turmeric 1 to 2 kg is the curcumin extract. The main medicinal / bioactive components of curcumin is known as curcuminoids
  • Curcuminoids comprise of curcumin, monodemethoxycurcumin and bisdemethoxycucumin which are found to be natural antioxidant and gives the yellow colour to the powder.
  • Volatile oil is responsible for the aroma of turmeric and it consists of aromatic (containing benzene ring) compounds out of which tumerone and ar-tumerone are considered medicinally quite important.
  • Sugars, proteins and resins are also isolated from the rhizome.

Numerous in vitro and in vivo studies have provided strong evidence for investigating curcumin (an extract of turmeric) efficacy against type 2 diabetes mellitus. Data reported in this review show that curcumin has therapeutic potential to counteract diabetes and its complications. All the described studies have shown that doses of up to 12g per day of curcumin are safe, tolerable and non-toxic. The functional mechanism by which curcumin exerts its effect appears to be the modulation of many signalling molecules.

Curcumim in Diabetes

Curcumim in Diabetes

  • Curcumin counteracts inflammation.
  • Curcumin decreases oxidative stress.
  • Curcumin lowers blood sugar levels.
  • Curcumin can repair and regenerate pancreatic cells.
  • Curcumin can reverse pre-diabetics.
  • Curcumin has an Anti- diabetogenesis effect.
Curcumin in diabetic complications

Curcumin in diabetic complications

  • Diabetic Nephropathy
  • Diabetic Retinopathy.
  • Microgiopathy.
  • Diabetes Gastroparesis.
  • Metabolic Syndrome.
  • Fatty Liver Disease.
  • Cardiovascular problems.
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  • Diabetic Nephropathy.
  • Diabetic Retiropathy.
  • Diabetic Neuropathy.
  • Cardiovasculas Risks.

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Numerous studies have shown that curcumin possesses a wide spectrum of biological and pharmacological properties, acting, for example, as anti-inflammatory, anti-angiogenic and anti-neoplastic, while no toxicity is associated with the compound. Curcumin supplements are shown to be very active against viral infections as well.

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